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Metabolic pathways engaged by antigen-specific T and B cells after SARS-CoV-2 vaccination in multiple sclerosis patients on different immunomodulatory drugs reveal immunosenescence and predict vaccine efficacy.

2023-11-17

Abstract excerpt

<title>Abstract</title><p>Disease modifying therapies (DMT) assumed by patients affected by multiple sclerosis (MS) can influence immune response to SARS-CoV-2 and vaccination efficacy. Even if in most treated patients vaccine-induced humoral and cellular responses can be attenuated, scanty data exist on detailed phenotypic, functional and metabolic characteristics of antigen (Ag)-specific cells following the thir...

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Literature Corpus work
112eb275-5116-53d5-ae2d-acf2c198c956
DOI
10.21203/rs.3.rs-3604561/v1
Open publication

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Metabolic pathways engaged by antigen-specific T and B cells after SARS-CoV-2 vaccination in multiple sclerosis patients on different immunomodulatory drugs reveal immunosenescence and predict vaccine efficacy.DOI 10.21203/rs.3.rs-3604561/v1
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