Article

Development of an improved reverse genetics system for avian metapneumovirus (aMPV): A novel vaccine vector protects against aMPV and infectious bursal disease virus

2024-04-12

Abstract excerpt

Avian metapneumovirus (aMPV), a paramyxovirus, causes acute respiratory diseases in turkeys and swollen head syndrome in chickens. This study established a reverse genetics system for aMPV subtype B LN16-A strain based on T7 RNA polymerase. Full-length cDNA of the LN16-A strain was constructed by assembling five cDNA fragments between the T7 promoter and hepatitis delta virus ribozyme. Transfection of this plasmid...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 10d07901-680b-5a9e-aac6-41918fa558bb
DOI: 10.1016/j.jia.2024.04.025

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development of an improved reverse genetics system for avian metapneumovirus (aMPV): A novel vaccine vector protects against aMPV and infectious bursal disease virusDOI 10.1016/j.jia.2024.04.025Read

Mutation of lysine 396 of the fusion protein reduces its binding affinity with integrin αVβ1 and leads to attenuation of avian metapneumovirus subtype B.Semantic proximity Read

Development of a Novel Avian Vaccine Vector Derived From the Emerging Fowl Adenovirus 4Semantic proximity Read

Recovery of Avian Metapneumovirus Subgroup C from cDNA: Cross-Recognition of Avian and Human Metapneumovirus Support ProteinsSemantic proximity Read

A Reverse Genetics Approach for the Design of Methyltransferase-Defective Live Attenuated Avian Metapneumovirus Vaccines.Semantic proximity Read

Development of a reverse genetics system for Getah virus and characterization of rescued strainsSemantic proximity Read

A comparison of AMPV subtypes A and B full genomes, gene transcripts and proteins led to reverse-genetics systems rescuing both subtypes.Semantic proximity Read

Characterization of avain metapneumovirus subgroup C isolated from chickens in Beijing, ChinaSemantic proximity Read

Reverse Genetics for Newcastle Disease Virus as a Vaccine VectorSemantic proximity Read

Establishment of an efficient reverse genetic system of Mumps virus S79 from cloned DNASemantic proximity Read

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and EfficacySemantic proximity Read

Rule of seven: a strategy for optimal propagation and innate immunity escape in human metapneumovirusSemantic proximity Read

Complete Genome Sequences of Avian Metapneumovirus Subtype B Vaccine Strains from BrazilSemantic proximity Read