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Article

Repair of cartilage defects in osteoarthritis rats with induced pluripotent stem cell derived chondrocytes

9 Nov 2016

Abstract excerpt

BACKGROUND: The incapacity of articular cartilage (AC) for self-repair after damage ultimately leads to the development of osteoarthritis. Stem cell-based therapy has been proposed for the treatment of osteoarthritis (OA) and induced pluripotent stem cells (iPSCs) are becoming a promising stem cell source. RESULTS: Three steps were developed to differentiate human iPSCs into chondrocytes which were transplanted...

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PMID: 27829414
DOI: 10.1186/s12896-016-0306-5

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