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Human mesenchymal stem cells overexpressing therapeutic genes: From basic science to clinical applications for articular cartilage repair

1 Jul 2012

Abstract excerpt

Adult articular cartilage has a limited capacity for self repair. Reproduction of a native structure and functional integrity in damaged cartilage remains a major problem in orthopaedic surgery. Strategies based on the implantation of genetically modified cells to sites of injury may provide workable options to treat articular cartilage lesions like those resulting from acute trauma or associated with the...

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PMID: 22785363
DOI: 10.3233/bme-2012-0709

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