Article

The effects of Stim1 and Orai1 expression levels on lymph node metastases and prognosis in patients with triple negative breast cancer

2024-01-12

Abstract excerpt

<title>Abstract</title> <bold>Objective:</bold> Calcium signaling pathways are closely related to breast cancer, including Calcium ions (Ca2+) metabolic disorders associated with cell proliferation and migration of triple-negative breast cancer (TNBC). The key proteins of store-operated Ca2+ entry (SOCE), Stromal interaction molecule 1 (Stim1) and calcium release-activated calcium channel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 100ddbf1-2b22-5ee0-bda8-9b2d91fcb4fb
DOI: 10.21203/rs.3.rs-3699654/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The effects of Stim1 and Orai1 expression levels on lymph node metastases and prognosis in patients with triple negative breast cancerDOI 10.21203/rs.3.rs-3699654/v1Read

STIM and ORAI proteins: crucial roles in hallmarks of cancerSemantic proximity Read

Targeting Stim and Orai Proteins as an Alternative Approach in Anticancer TherapySemantic proximity Read

Orai2 Modulates Store-Operated Ca2+ Entry and Cell Cycle Progression in Breast Cancer CellsSemantic proximity Read

Identification of Key Genes and Pathways in Triple-Negative Breast Cancer by Integrated Bioinformatics AnalysisSemantic proximity Read

CRAC channels, calcium, and cancer in light of the driver and passenger concept.Semantic proximity Read

Evaluation for the Genetic Association between Store-Operated Calcium Influx Pathway (STIM1 and ORAI1) and Human Hepatocellular Carcinoma in Patients with Chronic Hepatitis B InfectionSemantic proximity Read

SERPINA1is a direct estrogen receptor target gene and a predictor of survival in breast cancer patientsSemantic proximity Read

Orai1-mediated store-operated Ca2+ entry promotes cervical cancer progression through IL-6 signalingSemantic proximity Read

Understanding Stim-1 Regulatory Networks in Nasopharyngeal Cancer Using Functional, Transcriptomics, Proteomics, and in-silico ApproachesSemantic proximity Read

Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connectionSemantic proximity Read

The association between single-nucleotide polymorphisms of ORAI1 gene and breast cancer in a Taiwanese population.Semantic proximity Read

CTPS1 Promotes Malignant Progression of Triple-Negative Breast Cancer With Transcriptional Activation By YBX1Semantic proximity Read