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Article

Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection

11 Jan 2018

Abstract excerpt

Orai proteins are highly selective calcium channels playing an important role in calcium entry. Orai3 channels are overexpressed in breast cancer (BC) tissues, and involved in their proliferation, cell cycle progression and survival. Herein, we sought to address the involvement of Orai3 in resistance to chemotherapeutic drugs. Using high-throughput approaches, we investigated major changes induced by Orai3...

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Bioactive Compounds and Antitumor Agents
Ion Channels and Receptors
Phytochemicals and Antioxidant Activities

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29323264
DOI: 10.1038/s41418-017-0007-1

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