Article

A horizontally acquired cyclic di-GMP phosphodiesterase regulated by zinc and quorum sensing

2025-04-28

Abstract excerpt

The second messenger cyclic di-GMP (cdG) in V. cholerae is indispensable for the regulation of biofilm formation, motility, and a variety of other important bacterial behaviors in the majority of bacteria. The human pathogen Vibrio cholerae has a diverse repertoire of diguanylate cyclase (DGC) and phosphodiesterase (PDE) enzymes that control the intracellular cdG concentration depending on local environmental cu...

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Literature Corpus work: 0fc1c830-8f4b-56d7-96bd-f32a03c58308
DOI: 10.1101/2025.04.25.650742

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