Back to search

Article

Validation and characterization of a DNA methylation alcohol biomarker across the life course

2019-03-28

Abstract excerpt

Recently, an alcohol predictor was developed using DNA methylation at 144 CpG sites (DNAm-Alc) as a biomarker for improved clinical or epidemiologic assessment of alcohol-related ill health. We validate the performance and characterize the drivers of this DNAm-Alc for the first time in independent populations. In N=1,049 parents from the Avon Longitudinal Study of Parents and Children (ALSPAC) Accessible Resource...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0f521f18-45e0-51e7-ab76-55ae8ed6346e
DOI
10.1101/591404
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Validation and characterization of a DNA methylation alcohol biomarker across the life courseDOI 10.1101/591404
Validation and characterisation of a DNA methylation alcohol biomarker across the life courseSemantic proximity
Alcohol consumption is associated with widespread changes in blood DNA methylation: analysis of cross-sectional and longitudinal dataSemantic proximity
Blood-based DNA methylation study of alcohol consumptionSemantic proximity
Long-term alterations to DNA methylation as a biomarker of prenatal alcohol exposure: From mouse models to human children with fetal alcohol spectrum disordersSemantic proximity
Alcohol consumption is associated with widespread changes in blood DNA methylation: Analysis of cross‐sectional and longitudinal dataSemantic proximity
Human genetics and epigenetics of alcohol use disorder.Semantic proximity
Epigenetics of alcohol use disorder-A review of recent advances in DNA methylation profiling.Semantic proximity
A DNA methylation biomarker of alcohol consumptionSemantic proximity
Validating biomarkers and models for epigenetic inference of alcohol consumption from bloodSemantic proximity
DNA Methylation Signature on Phosphatidylethanol, not Self-Reported Alcohol Consumption, Predicts Hazardous Alcohol Consumption in Two Distinct PopulationsSemantic proximity
A DNA methylation biomarker of alcohol consumptionSemantic proximity
Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites.Semantic proximity
Select a neighboring publication to make it the new centre.