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Article

Validation and characterisation of a DNA methylation alcohol biomarker across the life course

27 Nov 2019

Abstract excerpt

BACKGROUND: Recently, an alcohol predictor was developed using DNA methylation at 144 CpG sites (DNAm-Alc) as a biomarker for improved clinical or epidemiologic assessment of alcohol-related ill health. We validate the performance and characterise the drivers of this DNAm-Alc for the first time in independent populations. RESULTS: In N = 1049 parents from the Avon Longitudinal Study of Parents and Children...

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PMID: 31775873
DOI: 10.1186/s13148-019-0753-7

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