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Article

Monogenic autoinflammatory disorders: Conceptual overview, phenotype, and clinical approach.

The Journal of allergy and clinical immunology - 1 Nov 2020

Nigrovic Peter A, Lee Pui Y, Hoffman Hal M

Abstract excerpt

Autoinflammatory diseases are conditions in which pathogenic inflammation arises primarily through antigen-independent hyperactivation of immune pathways. First recognized just over 2 decades ago, the autoinflammatory disease spectrum has expanded rapidly to include more than 40 distinct monogenic conditions. Related mechanisms contribute to common conditions such as gout and cardiovascular disease. Here, we...

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Identifiers

PMID: 33160483
DOI: 10.1016/j.jaci.2020.08.017
PMCID: PMC7727443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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