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DFB Suppresses Obesity-Driven CRC Via Restricting Progenitor to Terminally Exhausted T Cell Differentiation

2021-10-19

Abstract excerpt

<h4>Background: </h4> Obesity contributes to about 30% incidence of colorectal cancer (CRC). Obese tumor microenvironment compromises anti-tumor immunity by eliciting exhausted T cells (Tex). Hypothesizing that Dahuang Fuzi Baijiang Decoction (DFB), a combined classical prescription from “Synopsis of Golden Chamber”, modulates the differentiation of tumor-infiltrating CD8 + T cells <h4>Methods: </h4>: Our present...

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Literature Corpus work
0e5e1059-83b5-5977-b6b6-37b6942afc85
DOI
10.21203/rs.3.rs-952538/v1
Open publication

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DFB Suppresses Obesity-Driven CRC Via Restricting Progenitor to Terminally Exhausted T Cell DifferentiationDOI 10.21203/rs.3.rs-952538/v1
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