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Article

Cardiovascular Health and Outcomes in Carriers With Genetic Variants of Hypertrophic Cardiomyopathy.

Mayo Clinic proceedings - 1 Jan 2026

Patel Nirav, Gaonkar Mokshad, Pampana Akhil, Dhaliwal Jasninder S, Vekariya Nehal, Shetty Naman S, Li Peng, Kalra Rajat, Arora Garima, Arora Pankaj

Abstract excerpt

OBJECTIVE: To elucidate the interplay between genetic predisposition and cardiovascular health (CVH) factors in individuals with pathogenic or likely pathogenic variants in hypertrophic cardiomyopathy sarcomere-encoding genes (SARC-HCM-P/LP). METHODS: This retrospective cohort study used data from the UK Biobank, including 159,375 participants aged 40 to 69 years with whole exome sequencing data and no baseline...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40704931
DOI: 10.1016/j.mayocp.2024.12.018
PMCID: PMC13229500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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