Article

Construction of recombinant Lactococcus expressing thymosin and interferon fusion protein and its application as an immune adjuvant

2022-11-10

Abstract excerpt

In this study, recombinant food-grade Lactococcus lactis (r- L. lactis -Tα1-IFN) expressing thymosin Tα1 and interferon fusion protein was constructed. In vitro interaction with macrophages showed that recombinant r- L. lactis -Tα1-IFN could significantly activate both macrophage J774-Dual™ NF-κB signaling pathway and IRF signaling pathway. In vitro interaction with chicken, PBMCs showed that recombinant r- L. lac...

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Literature Corpus work: 0e07b7ec-27da-518f-8a4e-884da78b6172
DOI: 10.21203/rs.3.rs-2242889/v1

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