Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast Cancer

30 Sept 2019

Abstract excerpt

Abstract The Newcastle disease virus (NDV) strain AF2240 is an avian avulavirus that has been demonstrated to possess oncolytic activity against cancer cells. However, to illicit a greater anti-cancer immune response, it is believed that the incorporation of immunostimulatory genes such as IL12 into a recombinant NDV backbone will enhance its oncolytic effect. In this study, a newly developed recombinant NDV that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Animal Virus Infections Studies
Share to Virology and Viral Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31570732
DOI: 10.1038/s41598-019-50222-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of a Recombinant Newcastle Disease Virus Expressing Human IL12 against Human Breast CancerPMID 31570732Read ↗

Newcastle disease virus strain AF2240 as an oncolytic virus: A reviewSemantic proximity Read ↗

Molecular mechanisms of oncolytic properties of Newcastle disease virus (NDV) in human cancer cellsSemantic proximity Read ↗

Investigation of oncolytic effect of recombinant Newcastle disease virus in primary and metastatic oral melanomaSemantic proximity Read ↗

The Application of Newcastle Disease Virus (NDV): Vaccine Vectors and Tumor TherapySemantic proximity Read ↗

Genetic Modification of Oncolytic Newcastle Disease Virus for Cancer TherapySemantic proximity Read ↗

Construction of Recombinant Newcastle Disease Virus Italien Strain for Oncolytic Virotherapy of TumorsSemantic proximity Read ↗

A Common Live-Attenuated Avian Herpesvirus Vaccine Expresses a Very Potent OncogeneSemantic proximity Read ↗

Apoptin Enhances the Oncolytic Properties of Newcastle Disease VirusSemantic proximity Read ↗

Human tumor cell modification by virus infection: an efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virusSemantic proximity Read ↗

hCCL19-expressing recombinant Newcastle disease virus boosts CAR T cell infiltration and efficacy in solid tumorSemantic proximity Read ↗

Recombinant Newcastle disease virus expressing human interleukin-2 serves as a potential candidate for tumor therapySemantic proximity Read ↗

A NDV-Based Platform for Vaccine and Oncolytic Virus DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.