Article

Immune response and resistance of clear cell renal cell carcinoma patients following immune checkpoint blockade

2023-10-08

Abstract excerpt

175,000 patients die because of renal cell carcinoma (RCC) each year. Clear cell renal cell carcinoma (ccRCC or KIRC) is the most frequent subtype of RCC. Current therapies include immune checkpoint inhibitors (ICB) or VEGFR tyrosine kinase inhibitors (TKIs). However, many patients did not respond to ICB and immune resistance still occurred. Immune resistance may be explained by expression of various immune checkp...

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Literature Corpus work: 0dcf7da3-4796-5ef6-9f70-6c198e45425b
DOI: 10.1101/2023.10.05.561140

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