Strategies for Generating Diverse Antibody Repertoires Using Transgenic Animals Expressing Human Antibodies

Abstract excerpt

Therapeutic molecules derived from antibodies have become a dominant class of drugs used to treat human disease. Increasingly, therapeutic antibodies are discovered using transgenic animal systems that have been engineered to express human antibodies. While the engineering details differ, these platforms share the ability to raise an immune response that is comprised of antibodies with fully human idiotypes....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Monoclonal and Polyclonal Antibodies Research
• Share to Transgenic Plants and Applications
• Share to Viral Infectious Diseases and Gene Expression in Insects