Article

Improved binding affinity of the Omicron’s spike protein with hACE2 receptor is the key factor behind its increased virulence

2021-12-28

Abstract excerpt

The new variant of SARS-CoV-2, Omicron, has been quickly spreading in many countries worldwide. Compared to the original virus, Omicron is characterized by several mutations in its genomic region, including spike protein’s receptor-binding domain (RBD). We have computationally investigated the interaction between RBD of both wild-type and omicron variants with hACE2 receptor using molecular dynamics and MM-GBSA ba...

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Literature Corpus work: 0d81c9b7-c351-5e64-902d-9c3d4e4c4f1f
DOI: 10.1101/2021.12.28.474338

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