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Article

An Optimized Method for LC-MS Based Quantification of Endogenous Organic Acids: Metabolic Perturbations in Pancreatic Cancer

2024-04-08

Abstract excerpt

Metabolomics profiling for accurate and reliable quantification of organic acids that carry a carboxylic acid functional group in complex biological samples, remains a major analytical challenge in clinical chemistry research. Several procedural barriers associated with quantification of clinically important carboxylic containing metabolites (CCMs) including spontaneous decarboxylation during ionization, poor chro...

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Literature Corpus work
0d634da4-85d8-5874-b616-c88b578b7473
DOI
10.20944/preprints202404.0528.v1
Open publication

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An Optimized Method for LC-MS Based Quantification of Endogenous Organic Acids: Metabolic Perturbations in Pancreatic CancerDOI 10.20944/preprints202404.0528.v1
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