Article

The structure-function relationship of atheroprotective ApoA-I mutants in high-density lipoproteins

2021-01-01

Abstract excerpt

In atherosclerosis cholesterol accumulation in arterial walls forms plaques which lead to associated cardiovascular diseases. High-density lipoprotein (HDL) nanoparticles known as ~good cholesterol~ transport cholesterol from arterial plaques to the liver for excretion. Therefore, HDL and its components have been targeted for tackling atherosclerosis treatment. Significantly, carriers of the R173C or L144R mutatio...

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Literature Corpus work: 0d58e2b8-04c9-5851-9983-2b7939af24ab
DOI: 10.17635/lancaster/thesis/1381

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