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Article

Positive impact of high-throughput drug sensitivity assay and salvage autologous CD19 CAR-T therapy on second marrow relapse of acute lymphoblastic leukemia with NT5C2 mutation

2022-04-04

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Recently, the five-year survival rate of pediatric acute lymphoblastic leukemia (ALL) has reached 90%. However, recurrence remains common following treatment. Recently, chimeric antigen receptor (CAR)-T cell immunotherapy has been shown to be effective in control of relapsed/refractory B-cell malignancies. Although lymphocyte-depleting conditioning chemotherapy,...

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Literature Corpus work
0d54f71b-6731-5bfe-b8a9-6441cc66d031
DOI
10.21203/rs.3.rs-1399753/v1
Open publication

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Positive impact of high-throughput drug sensitivity assay and salvage autologous CD19 CAR-T therapy on second marrow relapse of acute lymphoblastic leukemia with NT5C2 mutationDOI 10.21203/rs.3.rs-1399753/v1
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