Article
Oncogenic RAS drives rapid onset cellular plasticity and elicits a tumour-promoting neutrophil response at the inception of preneoplastic development
2023-11-13
Abstract excerpt
To date, very little is known regarding the earliest cellular and molecular events within the initial preneoplastic cell (PNC) niche that might determine the outcome of PNC development. Here, we combine in vivo live imaging and single cell transcriptomics to investigate the immediate cellular and molecular changes that occur in PNCs and responding innate immune cells within the first 24 hours following tumour ini...
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Identifiers and source
- Literature Corpus work
- 0d2c0313-df0a-5760-aa87-2e6e7fadc124
- DOI
- 10.1101/2023.11.10.566547
