Article

Do ERBB Receptors Serve as a Nexus for Oncogenic Signals in Uveal Melanoma?

2026-04-01

Abstract excerpt

Uveal melanomas (UMs) metastasize at a high frequency, and metastatic UMs are associated with very poor clinical outcomes. Consequently, there is considerable interest in the genetics and biochemistry of UM and how these insights may lead to novel and effective approaches for treating UM. This work reviews evidence that elevated signaling by the CYSLTR2/Gaq/Ga11 pathway drives UM. This work focuses on the large nu...

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Literature Corpus work: 0d01763a-6bf6-50ba-8a88-1632469a58e8
DOI: 10.20944/preprints202604.0001.v1

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