Article

The Ecoimmunology of Health and Disease: The Hygiene Hypothesis and Plasticity in Human Immune Function

2022-07-27

Abstract excerpt

The original hygiene hypothesis proposed that certain diseases derive from low levels of early-life microbial exposure. Since then, the hypothesis has been applied to numerous inflammatory, autoimmune, and allergic conditions. The changes in hygiene linked to these diseases include numerous changes in biotic exposure and lifestyle. To this end, some scholars have called for abandonment of the term or have suggeste...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0ceaa104-5630-5290-9cb7-75d728340348
DOI: 10.1146/annurev-anthro-101819-110236

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Ecoimmunology of Health and Disease: The Hygiene Hypothesis and Plasticity in Human Immune FunctionDOI 10.1146/annurev-anthro-101819-110236Read

The Hygiene Hypothesis - Learning From but Not Living in the Past.Semantic proximity Read

Hygiene and other early childhood influences on the subsequent function of the immune system.Semantic proximity Read

Gene/environment interaction and autoimmune diseaseSemantic proximity Read

Revisiting the Hygiene Hypothesis in the Context of AutoimmunitySemantic proximity Read

Immuno-ecology: how the microbiome regulates tolerance and autoimmunitySemantic proximity Read

Mechanisms of the hygiene hypothesis--molecular and otherwise.Semantic proximity Read

Autoimmune Diseases in the Interpretation of Evolutionary MedicineSemantic proximity Read

The Autoimmune EcologySemantic proximity Read

Defining dysbiosis and its influence on host immunity and diseaseSemantic proximity Read

Early environments and the ecology of inflammation.Semantic proximity Read

Ecoimmunity: immune tolerance by symmetric co-evolution.Semantic proximity Read

The influence of the microbiota on immune development, chronic inflammation, and cancer in the context of agingSemantic proximity Read