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Defining dysbiosis and its influence on host immunity and disease

5 May 2014

Abstract excerpt

Mammalian immune system development depends on instruction from resident commensal microorganisms. Diseases associated with abnormal immune responses towards environmental and self antigens have been rapidly increasing over the last 50 years. These diseases include inflammatory bowel disease (IBD), multiple sclerosis (MS), type I diabetes (T1D), allergies and asthma. The observation that people with immune...

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PMID: 24798552
DOI: 10.1111/cmi.12308

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