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Article

The Hygiene Hypothesis - Learning From but Not Living in the Past.

Frontiers in immunology - 1 Jan 2021

Pfefferle Petra I, Keber Corinna U, Cohen Robert M, Garn Holger

Abstract excerpt

Postulated by Strachan more than 30 years ago, the Hygiene Hypothesis has undergone many revisions and adaptations. This review journeys back to the beginnings of the Hygiene Hypothesis and describes the most important landmarks in its development considering the many aspects that have refined and generalized the Hygiene Hypothesis over time. From an epidemiological perspective, the Hygiene Hypothesis advanced to...

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Identifiers

PMID: 33796103
DOI: 10.3389/fimmu.2021.635935
PMCID: PMC8007786

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