Article

Beta Adrenergic Signaling as a Therapeutic Target for Autoimmunity

2025-04-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> We recently identified a molecular mechanism involving beta-adrenergic 1 and 2 receptors (β1/2) in the development of T H 17 lymphocytes. Pharmacological and genetic inhibition of these receptors in combination, but not separately, impaired the ability of T-lymphocytes to produce proinflammatory interleukin 17A (IL-17A) and instead promoted the production of protective T r...

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Literature Corpus work: 0cbdde44-417e-5a40-89e9-e7d87fffeaf2
DOI: 10.1101/2025.04.05.647384

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