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Lineages derived from <i>Cryptococcus neoformans</i> type strain H99 support a link between the capacity to be pleomorphic and virulence

2022-02-10

Abstract excerpt

<h4>ABSTRACT</h4> The pathogenic yeast Cryptococcus neoformans causes nearly 200,000 deaths annually in immunocompromised individuals. Cryptococcus cells can undergo substantial morphological change during mammalian infection, including increased capsule and cell size, the release of shed capsule, and the production of titan (> 10 μm), micro (< 2 μm) and irregular cells. We examined phenotypic variation under c...

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Literature Corpus work
0c71d486-8aa9-5b7a-9910-6d08ffa9fa10
DOI
10.1101/2022.02.09.479843
Open publication

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