Back to search

Article

Bioequivalence Evaluation of Generic Febuxostat versus Feburic ® in Healthy Chinese Subjects: A Randomized Crossover Study

2025-05-21

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold> Febuxostat, a xanthine oxidase inhibitor, is a first-line treatment for gout with hyperuricemia. This study evaluated the pharmacokinetic (PK) bioequivalence, safety profile, and food effects of a generic febuxostat formulation compared to the reference product (Feburic®) in healthy Chinese volunteers <bold>Patients and Methods</bold> In this randomized, open-label,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
0c67d2c3-ca3a-51d5-a186-4376b704fbf1
DOI
10.21203/rs.3.rs-6492168/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Bioequivalence Evaluation of Generic Febuxostat versus Feburic ® in Healthy Chinese Subjects: A Randomized Crossover StudyDOI 10.21203/rs.3.rs-6492168/v1
Safety and efficacy of oral febuxostat for treatment of HLA-B*5801-negative gout: a randomized, open-label, multicentre, allopurinol-controlled study.Semantic proximity
Bioequivalence Study of Azilsartan in Healthy Chinese SubjectsSemantic proximity
Pharmacokinetics and Bioequivalence of Two Formulations of Omeprazole and Sodiun bicarbonate powder, for suspension: A Randomized, Single-Dose, Two-Period, Two-Sequence Crossover Study in Healthy Chinese VolunteersSemantic proximity
Pharmacokinetics and Bioequivalence of Sitagliptin Phosphate/Metformin Hydrochloride Tablets in Healthy Chinese Subjects: A Randomized, Open, Crossover StudySemantic proximity
Pharmacokinetics and bioequivalence of two formulations of rebamipide 100-mg tablets: a randomized, single-dose, two-period, two-sequence crossover study in healthy Korean male volunteers.Semantic proximity
Investigation on modulation of human P-gp by multiple doses of Radix Astragali extract granules using fexofenadine as a phenotyping probe.Semantic proximity
Pharmacokinetics and bioavailability comparison of generic and branded citalopram 20 mg tablets: an open-label, randomized-sequence, two-period crossover study in healthy Chinese CYP2C19 extensive metabolizers.Semantic proximity
Effect of food and polymorphisms in SLCO2B1, CYP3A4 and UGT1A4 on pharmacokinetics of abiraterone and its metabolites in Chinese volunteers.Semantic proximity
Pharmacokinetics and Bioequivalence Study of Two Ciprofloxacin&nbsp;Hydrochloride&nbsp;Tablets in Chinese Healthy Volunteers Under Fasting and Fed Conditions: A Randomized, Open-Label, Two-Formulation, Two-Sequence, Two-Period, Single-Dose Crossover Study.Semantic proximity
Application of a physiologically based pharmacokinetic model for the evaluation of single-point plasma phenotyping method of CYP2D6.Semantic proximity
Pharmacokinetics and Bioequivalence of Two Formulations of Azithromycin Tablets: A Randomized, Single Dose, 3-Period Crossover Study in Healthy Chinese Volunteers Under Fasting and Fed ConditionsSemantic proximity
Effect of ABCG2 genotypes on the pharmacokinetics of A771726, an active metabolite of prodrug leflunomide, and association of A771726 exposure with serum uric acid level.Semantic proximity
Select a neighboring publication to make it the new centre.