Article

Out of sight, out of mind? Germ cells and the potential impacts of epigenomic drugs

2018-12-21

Abstract excerpt

Epigenetic modifications, including DNA methylation and histone modifications, determine the way DNA is packaged within the nucleus and regulate cell-specific gene expression. The heritability of these modifications provides a memory of cell identity and function. Common dysregulation of epigenetic modifications in cancer has driven substantial interest in the development of epigenetic modifying drugs. Although th...

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Literature Corpus work: 0c401e69-73ba-5946-86d3-d37644f564cb
DOI: 10.12688/f1000research.15935.1

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