Article

MT2A Promotes Angiogenesis in Chronically Ischemic Brains through a Copper–Mitochondria Regulatory Mechanism

2024-12-02

Abstract excerpt

<title>Abstract</title> <p>Background Recent studies have indicated that copper overload (CPO) has cytotoxic effects, and metallothionein 2A (MT2A) has a high affinity for metal ions. However, it is unclear whether MT2A can normalize endothelial cell (EC) proliferation and angiogenesis in chronically ischemic brains by neutralizing excessive copper ions during CPO. Methods Dura matter (DM) samples from patients...

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Literature Corpus work: 0bbc4862-6118-5aeb-a76a-5bbf6e980af4
DOI: 10.21203/rs.3.rs-5230190/v1

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