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Copper metabolism and cuproptosis in human malignancies: Unraveling the complex interplay for therapeutic insights

1 Mar 2024

Abstract excerpt

Copper, a vital trace element, orchestrates diverse cellular processes ranging from energy production to antioxidant defense and angiogenesis. Copper metabolism and cuproptosis are closely linked in the context of human diseases, with a particular focus on cancer. Cuproptosis refers to a specific type of copper-mediated cell death or copper toxicity triggered by disruptions in copper metabolism within the cells....

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PMID: 38486750
DOI: 10.1016/j.heliyon.2024.e27496

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