Article

A Graph-Informed Modeling Framework Empowering Gene Pathway Discovery

2024-09-25

Abstract excerpt

This study introduces a novel graph-informed modeling framework for improving the statistical analysis of gene expression data, particularly in the context of identifying differentially expressed gene pathways and gene expression-assisted disease classification in a high-dimensional data setting. By integrating gene regulatory network information into hypothesis testing for the difference between mean vectors and...

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Literature Corpus work: 0ba0b753-5ad9-53d9-80ed-020a285f676a
DOI: 10.1101/2024.09.24.614661

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