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Evaluation of a Biplanar Vector-Based Diagnostic Model for Subthreshold Disease: In Silico Stress Testing of Composite Drift Score Performance Under Stochastic, 2D, and 3D Conditions

2025-06-20

Abstract excerpt

<h4>ABSTRACT</h4> Traditional threshold-based diagnostics often miss early disease progression, particularly in subthreshold states. In a prior model, we proposed the Composite Drift Score (CDS), a vector-based index that quantifies directional drift from physiological norms. This metric uses two components: the Magnitude-to-Noise Ratio (MNR) and a Directional Emphasis Multiplier (DEM). This study stress-tests the...

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Literature Corpus work
0b55bc89-a61f-5a67-9c9f-d2d12b8b5342
DOI
10.1101/2025.06.19.25329940
Open publication

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Evaluation of a Biplanar Vector-Based Diagnostic Model for Subthreshold Disease: In Silico Stress Testing of Composite Drift Score Performance Under Stochastic, 2D, and 3D ConditionsDOI 10.1101/2025.06.19.25329940
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