Article

Temporal-deviation-driven community detection uncovers early-warning signals for critical transitions in complex diseases

2026-05-12

Abstract excerpt

Early detection of critical transitions in complex diseases is crucial for timely clinical intervention. However, as patients often provide only a single snapshot, identifying sample-specific early-warning signals (EWS) from a dynamical evolution perspective remains challenging, coupled with high-dimensional noise amplification. Here, we present TD-COM, a framework for detecting personalized EWS of critical transi...

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Literature Corpus work: 73fc27bd-13b8-5916-86b4-b8e6fe4a67ac
DOI: 10.64898/2026.05.08.723925

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