Article

Natural history of retinitis pigmentosa based on genotype, vitamin A/E supplementation, and an electroretinogram biomarker

2022-11-29

Abstract excerpt

A randomized clinical trial that began in 1984 was conducted to determine the efficacy of vitamin A and E supplementation to reduce the rate of disease progression in patients with retinitis pigmentosa (RP). Vitamin A was shown to provide benefit while vitamin E had an adverse effect. Although genetic testing was unavailable at that time, banked DNA samples now provide the opportunity to combine modern genetic cla...

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Literature Corpus work: 0b11f22a-41be-544e-b855-2d68ed834ed4
DOI: 10.1101/2022.11.26.22282587

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