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Article

T-cell responses in chronic myeloid leukaemia

2005-01-01

Abstract excerpt

Chronic Myeloid Leukaemia (CML) is a malignant clonal disorder of haematopoietic stem cells characterised by a reciprocal chromosomal translocation t(9; 22) that leads to the formation of a novel hybrid BCR-ABL fusion gene. One of the two major types, b2a2 or b3a2, is found in most CML patients. Peptides derived from the fusion junction of BCR-ABL can potentially act as a target for T lymphocyte-mediated immune re...

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Literature Corpus work
0aefd520-cb9b-532d-9063-adac4c70dfbc
DOI
10.17638/03167741
Open publication

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