Article

14-3-3β paralog is inhibited by acetylation during differentiation to the osteogenic lineage

2019-12-17

Abstract excerpt

14-3-3 protein family binds and regulate hundred of serine/threonine phosphorylated proteins. Considered as redundant, ubiquitous and constantly expressed this protein family was treated as an accessory for many signaling systems. Here we studied the reversible inhibition by acetylation of its essential N-ε-lysine 49/51 residue during the osteogenic differentiation of human adipose-derived stem cells (ASC). We fou...

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Literature Corpus work: 0ae02fd5-d09b-50fe-bca1-24b07decd52a
DOI: 10.1101/2019.12.17.879155

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