Back to search

Article

Glycoproteome remodelling in MLL-rearranged B-cell precursor acute lymphoblastic leukemia

2021-06-30

Abstract excerpt

B-cell precursor acute lymphoblastic leukemia (BCP-ALL) with mixed-lineage leukemia gene rearrangement (MLL-r) is a poor-prognosis subtype for which additional therapeutic targets are urgently needed. Currently no multi omics data set for primary MLL r patient cells exists that integrates transcriptomics, proteomics and glycomics to gain an inclusive picture of theranostic targets. <h4>Methods</h4> We have integra...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e94d0acc-8f87-5401-9b13-835e6e57f4e4
DOI
10.1101/2021.06.25.21259296
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Glycoproteome remodelling in MLL-rearranged B-cell precursor acute lymphoblastic leukemiaDOI 10.1101/2021.06.25.21259296
Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemiaSemantic proximity
The Origin, Diagnosis, and Prognosis of Oligomannose-Type Diffuse Large B-Cell LymphomaSemantic proximity
Integrated N- and O-Glycomics of Acute Myeloid Leukemia (AML) Cell LinesSemantic proximity
The origin, diagnosis, and prognosis of oligomannose-type diffuse large B-cell lymphomaSemantic proximity
Application of Omics Analyses in Pediatric B-Cell Acute Lymphoblastic LeukemiaSemantic proximity
Proteomics in Childhood Acute Lymphoblastic Leukemia: Challenges and OpportunitiesSemantic proximity
Insertion of atypical glycans into the tumor antigen-binding site identifies DLBCLs with distinct origin and behaviorSemantic proximity
The transcriptional landscape of glycosylation-related genes in cancerSemantic proximity
Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomicsSemantic proximity
A glycosylation-related signature can predict prognosis and immunotherapy response in patients with acute myeloid leukaemiaSemantic proximity
Key Cancer Glycosylation-related Genes Analysis: Regulatory, Therapeutic, and Prognostic InsightsSemantic proximity
Proteogenomics refines the molecular classification of chronic lymphocytic leukemiaSemantic proximity
Select a neighboring publication to make it the new centre.