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Origin recognition complex subunit 1(ORC1) is a potential biomarker and therapeutic target in cancer

13 Oct 2023

Abstract excerpt

BACKGROUND: The origin recognition complex 1 (ORC1) is a large subunit of the origin recognition complex and acts as the master subunit of the precoding complex. OBJECTIVE: To explore potential function and clinical significance of ORC1 in cancers. METHODS: The expression level of ORC1 in different types of tumor tissues and matched normal tissues were detected by The Cancer Genome Atlas (TCGA) and validated by...

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PMID: 37833711
DOI: 10.1186/s12920-023-01691-9

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