Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical relevance of ORCs in predicting prognosis and immunotherapy outcomes: A pan-cancer analysis.

Immunobiology - 1 Mar 2024

Zhao Yajun, Wang Jiangtao, Liang Xiaodong, Wang Chen

Abstract excerpt

BACKGROUND: The origin recognition complex (ORC) consists of six subunits and mediates DNA replication by binding to its origin. Recent studies show that ORCs are closely related to various biological processes in tumors. However, a comprehensive study of ORCs in pan-cancer has not been conducted. RESULTS: A systematic evaluation of the expression, mutation, and prognostic significance of ORCs was conducted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clinical Relevance
Share to Immunotherapy
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Prognosis

Source

Identifiers

PMID: 38211410
DOI: 10.1016/j.imbio.2024.152783

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical relevance of ORCs in predicting prognosis and immunotherapy outcomes: A pan-cancer analysis.PMID 38211410Read ↗

ORC6, a novel prognostic biomarker, correlates with T regulatory cell infiltration in prostate adenocarcinoma: a pan-cancer analysisSemantic proximity Read ↗

Origin recognition complex subunit 1(ORC1) is a potential biomarker and therapeutic target in cancerSemantic proximity Read ↗

Systemic analysis of the DNA replication regulator origin recognition complex in lung adenocarcinomas identifies prognostic and expression significanceSemantic proximity Read ↗

Origin Recognition Complex Subunit 1(ORC1) is a potential biomarker and therapeutic target in cancerSemantic proximity Read ↗

Multi-omic signatures identify pan-cancer classes of tumors beyond tissue of originSemantic proximity Read ↗

Systemic Analysis of the Dna Replication Regulators Origin Recognition Complex in Lung Adenocarcinomas Identifies Prognostic and Expression SignificanceSemantic proximity Read ↗

Pan-cancer analysis reveals embryonic and hematopoietic stem cell signatures to distinguish different cancer subtypesSemantic proximity Read ↗

Novel candidate biomarkers of origin recognition complex 1, 5 and 6 for survival surveillance in patients with hepatocellular carcinomaSemantic proximity Read ↗

DSCC1 Identified as Promising Tumor Biomarker and Potential Therapeutic Target Through Comprehensive Multi-omics Analysis and Experimental Validation.Semantic proximity Read ↗

A pan-cancer analysis of the oncogenic role of ERCC6LSemantic proximity Read ↗

ESCO2's Oncogenic Role in Human Tumors: A Pan-Cancer Analysis and Experimental ValidationSemantic proximity Read ↗

Origin recognition complex 6 overexpression promotes growth of glioma cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.