Article

Spatial Mapping of SARS-CoV-2 and H1N1 Influenza Lung Injury Identifies Differential Transcriptional Signatures

2020-08-14

Abstract excerpt

Severe SARS-CoV-2 infection often leads to development of acute respiratory distress syndrome (ARDS), with profound patho-histological changes in post-mortem lung tissues. However, there remains poor insight into the specific transcriptome expression within these damaged regions. We utilized a new spatial transcriptomic platform in ARDS lung tissue from patients with SARS-CoV-2, Influenza H1N1, or both viruses a...

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Literature Corpus work: 0a4753c8-9f9a-5323-9235-47cb8000bcdb
DOI: 10.2139/ssrn.3673600

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