Article

Mechanisms of pathogenesis of African pneumococcal serotype 1 isolates during nasopharyngeal carriage and invasive disease

2016-01-01

Abstract excerpt

Background: Streptococcus pneumoniae is a human pathogen responsible for serious diseases such as pneumonia, septicaemia and meningitis. There are over 90 pneumococcal serotypes, with serotype 1 being a major cause of invasive disease worldwide. Despite its high invasiveness, serotype 1 is rarely isolated during nasopharyngeal carriage. The aim of this study is to understand the various mechanisms that determine t...

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Literature Corpus work: 0a0a7144-b7f8-5070-99a1-f997696fde20
DOI: 10.17638/03000751

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