Article
Genetic Background Matters: Population-based Studies in Model Organisms for Translational Research
2022-05-24
Abstract excerpt
We are all similar, but a bit different. These differences are partially due to variations in our genomes and are related to the heterogeneity of symptoms and responses to treatments that patients exhibit. Most animal studies are performed in one single strain with one manipulation. However, due to the lack of variability, therapies are not always reproducible when treatments are translated to humans. Panels of al...
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Identifiers and source
- Literature Corpus work
- 09e54fb8-5cbb-5988-b708-b0d836a96c2d
- DOI
- 10.20944/preprints202205.0314.v1