The future of model organisms in human disease research.

Abstract excerpt

Model organisms have played a huge part in the history of studies of human genetic disease, both in identifying disease genes and characterizing their normal and abnormal functions. But is the importance of model organisms diminishing? The direct discovery of disease genes and variants in humans has been revolutionized, first by genome-wide association studies and now by whole-genome sequencing. Not only is it...

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• Chromosome Mapping
• Genetic Association Studies
• Genome, Human
• Models, Animal
• Models, Biological