Article

Application of a novel haplotype-based scan for local adaptation to study high-altitude adaptation in rhesus macaques

2020-05-22

Abstract excerpt

When natural populations split and migrate to different environments, they may experience different selection pressures that can lead to local adaptation. To capture the genomic patterns of a local selective sweep, we develop XP-nSL, a genomic scan for local adaptation that compares haplotype patterns between two populations. We show that XP-nSL has power to detect ongoing and recently completed hard and soft swee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 09c59a6d-9643-5ca8-ac79-6bf5bc748e09
DOI: 10.1101/2020.05.19.104380

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Application of a novel haplotype-based scan for local adaptation to study high-altitude adaptation in rhesus macaquesDOI 10.1101/2020.05.19.104380Read

Application of a novel haplotype-based scan for local adaptation to study high-altitude adaptation in rhesus macaquesSemantic proximity Read

The rhesus macaque is three times as diverse but more closely equivalent in damaging coding variation as compared to the human.Semantic proximity Read

Finding the genes underlying adaptation to hypoxia using genomic scans for genetic adaptation and admixture mapping.Semantic proximity Read

Localizing recent adaptive evolution in the human genome.Semantic proximity Read

Widespread signals of convergent adaptation to high altitude in Asia and america.Semantic proximity Read

Widespread signals of convergent adaptation to high altitude in Asia and AmericaSemantic proximity Read

Identifying positive selection candidate loci for high-altitude adaptation in Andean populations.Semantic proximity Read

The Genomics of Human Local Adaptation.Semantic proximity Read

Genetic mechanism of adaptive evolution: the example of adaptation to high altitudes.Semantic proximity Read

Genetic Signatures of Positive Selection in Human Populations Adapted to High Altitude in Papua New GuineaSemantic proximity Read

Ancient DNA reveals selection acting on genes associated with hypoxia response in pre-Columbian Peruvian Highlanders in the last 8500 years.Semantic proximity Read

New Insights into the Genetic Basis of Monge's Disease and Adaptation to High-Altitude.Semantic proximity Read