Article

Mechanism of CO <sub>2</sub> and NH <sub>3</sub> Transport through Human Aquaporin 1: Evidence for Parallel CO <sub>2</sub> Pathways

2025-03-03

Abstract excerpt

The traditional view had been that dissolved gases cross membranes simply by dissolving in and diffusing through membrane lipid. However, some membranes are impermeable to CO 2 and NH 3 , whereas some aquaporin (AQP) water channels—tetramers with hydrophobic central pores—are permeable to CO 2 , NH 3 , or both. Nevertheless, we understand neither the routes that CO 2 and NH 3 take through AQP tetramers, nor...

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Literature Corpus work: 09134c58-cbbe-5106-a30d-217db570fbd0
DOI: 10.1101/2025.02.28.640247

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