Article

Lack of accelerated ovarian aging in a follicle-stimulating hormone receptor haploinsufficiency model

2022-10-07

Abstract excerpt

Follicle-stimulation hormone (FSH) and FSH receptor (FSHR) signaling is essential for lifelong ovarian and endocrine functions in females. Previous studies have reported that Fshr haploinsufficiency in female mice led to accelerated ovarian aging, including anticipated progressive fertility decline, irregular estrus cycles, increased follicular atresia and premature ovarian failure at 7 to 9 months of age. Intere...

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Literature Corpus work: 0908adc8-eb2d-5b0a-b249-9cc78e78ad29
DOI: 10.1101/2022.10.07.511325

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