Article

Hair follicle stem cell fate supports distinct clinical endotypes in <i>Hidradenitis Suppurativa</i>

2025-06-01

Abstract excerpt

Hidradenitis suppurativa (HS) is a severe skin disorder affecting 1% of the global population, with a complex and poorly understood pathogenesis involving aberrant keratinization and autoinflammation. It remains unclear whether autoinflammatory events precede or follow hyperkeratotic changes in hair follicle (HF) epithelia. Using single-cell RNA sequencing, we characterized HF cell populations in HS patients and i...

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Literature Corpus work: 09023485-ca7e-547e-b4e3-4decf227b00b
DOI: 10.1101/2025.05.28.656362

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