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Article

Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Mar 2026

Onfroy Audrey, Jean-Louis Francette, Le Corvoisier Philippe, Coulpier Fanny, Muret Kévin, Bonnet Eric, Arrouasse Raphaele, Boucle Caroline, Abid Salwa, Sbidian Emilie, Bergqvist Christina, Wolkenstein Pierre, Godot Véronique, Deleuze Jean-François, Lévy Yves, Topilko Piotr, Audureau Etienne, Hue Sophie

Abstract excerpt

BACKGROUND: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting approximately 1% of the global population. Its pathogenesis involves both aberrant keratinization and autoinflammation, but the temporal relationship between these processes remains unclear. OBJECTIVES: To investigate the role of HF stem cell (HF-SC) fate in the early pathogenesis of HS. METHODS: We performed single-cell...

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Identifiers

PMID: 41195937
DOI: 10.1111/jdv.70152
PMCID: PMC12933698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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