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Identification and functional validation of ACSL1 as a biomarker regulating ferroptosis in nucleus pulposus cell

5 Mar 2025

Abstract excerpt

Intervertebral disc degeneration (IVDD) is a prevalent musculoskeletal disorder characterized by the deterioration of nucleus pulposus (NP) cells, leading to significant impairments in patients' quality of life. Elucidating the molecular mechanisms underlying IVDD is essential for developing effective therapeutic strategies. In this study, we utilized weighted gene co-expression network analysis to identify key...

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PMID: 40042449
DOI: 10.1042/bsr20241414

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